The dynamics of the supply chain system and the challenges that exist in today's small and medium enterprises (SME) environment are the definitions of technological progress and a world without borders facing every SME that yearns to excel. Many aspects related to SMEs and their supply chain need to be addressed so that SMEs can remain relevant and competitive in the face of challenges. The supply chain management aspect of SMEs is one of the important elements to ensure the stability and continuity of an organization in meeting the wishes and needs of its customers. To face the challenges of an SME'S management system, it requires an understanding of the relationship of the entire system and for all elements in the system to take comprehensive preventive and corrective measures in various phases of the challenge. This book collects and obtains input and views from scholars and professionals by examining the theoretical, practical implementation, and management challenges of supply chain management faced by SMEs. It is hoped that the production of this edited book can be a small guide for the various types of SMEs that are always faced with the challenges of globalization and technological progress in meeting the wishes and needs of their customers.