The rebirth of the race of man is closely watched, and the Selected, the transgenic humans created by the Moîrai, guide and care for the wellbeing of the remaining humans in their various Communities around the planet.

Peace and security are suddenly shattered with acts of sabotage disrupting the fragile equilibrium of the growing society. Betrayal, fear, and a cosmic conspiracy risk sending the planet to the brink of self-destruction. Will Dan Amenta be able to come to terms with the logic of alien minds? Who is behind the sabotage and why?

Death and blind violence walk in the secret alleys and in the depths of the planet, from the coldest lands to the bottom of the oceans; someone is at work with an evil agenda dictated by greed and lust for power. Ancient aliens, a galactic struggle, the control of a unique resource, meld to dictate the fate of humankind.

"Once Humans" starts seven years after the events narrated in "Daimones", Vol.1 of the homonymous "Daimones Trilogy".

The story is a 'loss of innocence' for Dan and for the Selected. The events and the emotional trauma prepare the race of man to reclaim its place in the galaxy.